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National Institute of Pharmaceutical Education and Research Hyderabad

Balanagar, Hyderabad-500037 ,Hyderabad

About Us

National Institute of Pharmaceutical Education and Research Hyderabad is an institute of National importance with a vision to serve as a leading global institution in the field of higher learning and research in Pharmaceutical Sciences and Management and to be one of the principal sources of professional manpower in the field for strengthening the Indian Pharma industry in obtaining quality products at affordable prices NIPER Hyderabad has secured 5th rank under Pharmacy Category in NIRF ranking 2020 The institute is well equipped with State of Art facilities for carrying out advanced research in the areas of pharmaceutical importance NIPER Hyderabad has published more than 584 publications in peer reviewed International National Journals and filed 12 patents Institute has also received 32 research projects from several government funding agencies like DST DBT Ayush ICMR etc to carry out research in different areas of Pharmaceutical sciences NIPER Faculties have received several prestigious awards such as Angelika Bierhaus award from NEURODIAB IDMA Young Pharmaceutical Analyst Award OPPI award Young scientist award from Telanagna Academy of Sciences and FICCI Award of Excellence Women in R&D etc The institute has established number of research collaborations with reputed national and international institutes and universities We have also entered into MoUs with leading institutes like IIT-BHU Varanasi National Institute for Micro Small and Medium Enterprises Hyderabad and Central Council for Research Institute of Unani Medicine Hyderabad & Research and Innovation Circle of Hyderabad Hyderabad Faculty members have considerable experience in carrying out translational projects

Area of Excellence

Drug Delivery Topical dermal drug delivery Process Chemistry Analytical Method Validation Pharcological screening and Pharmacodynamic evaluation Pharmacoinformatics Regulatory toxicology Development of Novel Treatment and Chemopreventive approaches with special emphasis on Ancient Indian Herbal medicine for management of Cancer and Diabetes Genotoxicological and Pharmacodynamic evaluation of Nanoparticles Microparticles liposomes phytosomes

Research Capability and Focus Area

Drug Delivery Topical dermal drug delivery Bioavailability enhancement Nano and microscaled drug delivery cargo development Targeted drug deliveries along with Novel platform technologies Neurodisorders Brain injury analysis Green chemistry Exploration of new synthetic methodologies including Online Mechanistic Investigations by ESI MS/MS Analysis of structural features of peptides Genotoxicological evaluation

Notable Research / Publication

[1] Srikanth Gatadi, Srinivas Nanduri. New potential drug leads against MDR-MTB: A short review. Bioorganic Chemistry. 2020; 95, 103534. [2] Bhandari, S.; Sana, S.; Shankaraiah, N. Ring-Opening Cyclization of Activated Spiro-aziridine Oxindoles with Heteroarenes: A Facile Synthetic Approach to Spiro-oxindole Fused Pyrroloindolines. RSC Advances 2020, 10, 16101-16109. [3] Shankaraiah, N.; Sakla, A. P.; Laxmikeshav, K.; Tokala, R. Reliability of Click Chemistry on Drug Discovery: A Personal Account. Chem. Record 2020, 20, 253-272 [4] Bora, D, Tokala R, John SE, Prasanth, B. Shankaraiah N. Carboline directed regioselective hydroxylation by employing Cu(OAc)2 and mechanistic investigation by ESI-MS. Org. Biomol. Chem., 2020, 18, 2307-2311. [5] Yadav U, Sakla A.P, Tokala R, Nyalam ST; Khurana A, Digwal CS, Talla V, Godugu C, Shankaraiah N, Kamal A. Design and synthesis of 5-morpholino-thiophene-indole/oxindole hybrids as cytotoxic agents. ChemistrySelect 2020, 5, 4356-4363. [6] Donthiboina K, Mani GS, Shankaraiah N, Kamal A. Iodine-mediated oxidative annulation by C-C cleavage: A domino synthetic approach to quinazolinones and benzimidazo[1,2-c]quinazolines. ChemistrySelect 2020, 5, 3923-3928 [7] Bhandari S, Sakla AP, Shankaraiah N. FeCl3-Catalyzed Domino Reaction: A Mild Synthetic Approach to Spirooxindolo-2-iminothiazolidine Scaffolds. Chemistry Select 2020, 5, 2886-2891 [8] Manasa, K.L.; Pujitha, S.; Sethi, A.; Arifuddin, M.; Alvala, M.; Angeli, A.; Supuran, C.T. Synthesis and Biological Evaluation of Imidazo[2,1-b]Thiazole based Sulfonyl Piperazines as Novel Carbonic Anhydrase II Inhibitors. Metabolites 2020, 10, 136. [9] Goud, N.S.; Kanth Makani V. K; Pranay, J.; Alvala, R.; Qureshi, I. A.; Kumar, P.; Bharath, R. D.; Nagaraj, C.; Yerramsetty, S.; Pal-Bhadra, M.; Alvala, M. Synthesis, 18F-radiolabeling and apoptosis inducing studies of novel 4,7-disubstituted coumarins. Bioorg Chem. 2020, 97, 103663. [10] Saleem Yousuf Bhat, PeddapakaJagruthi, Angapelly Srinivas, Mohammed Arifuddin, Insaf Ahmed Qureshi. Synthesis of quinoline-carbaldehyde derivatives as novel inhibitors for leishmanial methionine aminopeptidase 1. Eur. J. Med. Chem. 2020, 186, 111860. [11] ManasaKadagathur, G. Parimala Devi, Preeti Grewal, Dilep Kumar Sigalapalli, Priyanka N. Makhal, Uttam Chand Banerjee, Nagendra Babu Bathini, Neelima D. Tangellamudia, Novel diindoloazepinone derivatives as DNA minor groove binding agents with selective topoisomerase I inhibition: Design, synthesis, biological evaluation and docking studies, Bioorg. Chem., 2020, 99, 103629. [12] Saiprasad N. Nunewar, Naveen Kotla, Jaya Lakshmi Uppu, Apoorva Dixit, Venkatesh Pooladanda, ChandraiahGodugu, Neelima D. Tangellamudi, Synthesis of 1-(Indol-2-yl)-phenoxazine hybrids from quinacetophenone precursors and their biological evaluation as DNA intercalating agent, J. Mol. Struct., 2020, 128311. [13] Daipule, Komal.; Goud, Nerella Sridhar.; Sethi, Aaftaab.; Gurrapu, Swapna; Mamidala, Estari; Alvala, Mallika; Synthesis, molecular docking simulation, and biological evaluation studies of novel amide and ether conjugates of 2, 3-diaryl-1, 3-thiazolidin-4-ones. Journal of Heterocyclic Chemistry, 2020, 57, 774-790. [14] Komal D, Joshi K, Sethi A, Soukya L, Alvala M. Targeting Integrase enzyme: A Therapeutic Approach to combat HIV resistance. Mini Rev. Med. Chem. 2020, 20, 219-238. [15] D Swain, AS Yadav, C Sasapu, V Akula, G Samanthula, UPLC Separation of forced degradation and process related impurities of Velpatasvir and structure elucidation by online LC-Quadrupole-Time of flight-Tandem mass Spectrometry. Microchemical Journal2020, 155, 104657. [16] Bhargavi Thalluri, Vivek Dhiman, Shristy Tiwari, ShandaliyaMahamuni Baira, MVN Kumar Talluri, Study on forced degradation behaviour of dofetilide by LC-PDA and Q-TOF/MS/MS: Mechanistic explanations of hydrolytic, oxidative and photocatalytic rearrangement of degradation products, Journal of pharmaceutical and biomedical analysis, 2020, 179, 112985. [17] Shristy S. Tiwari, Sumit Mukesh, Abhay T. Sangamwar, M.V.N. Kumar Talluri, In vivo metabolic investigation of Cetilistatin normal vs pseudo germ free rats by UPLC-Q-TOF/MS/MS and in silico toxicological evaluation of its metabolites. Biomedical Chromatography, 2020, e4860 [18] Shruti Surendran, Rekha Sapkal, David Paul, SatheeshkumarNanjappan. Effect of Resveratrol on Dipeptidyl peptidase-4 Inhibitors Pharmacokinetics: An In Vitro and In Vivo Approach. Chemico-Biological Interactions, 2020, 315, 108909. [19] Johnsirani P, Aabid Abdullah Wani, Prasad V Bharatam, SatheeshkumarNanjappan. LC-ESI-QTOF-MS analysis utilizing gas-phase fragmentation reactions subjected to ESI-IS-CID and ESI-CID-MS/MS conditions to study the degradation behaviour of sorafenib tosylate: NMR and in vitro cytotoxicity and apoptosis detection. Journal of Pharmaceutical and Biomedical Analysis, 2020, 177, 112881. [20] Bansod S, Aslam Saifi M, Khurana A, Godugu C. Nimbolide abrogates cerulein-induced chronic pancreatitis by modulating-catenin/Smad in a sirtuin-dependent way. Pharmacological research 2020,156, 104756. [21] Domala A, Bale S, Godugu C. Protective effects of nanoceria in imiquimod induced psoriasis by inhibiting the inflammatory responses. Nanomedicine 2020,15, 5-22. [22] Godugu C, Pasari LP, Khurana A, Anchi P, Saifi MA, Bansod SP. Crocin, an active constituent of Crocus sativus ameliorates cerulein induced pancreatic inflammation and oxidative stress. Phytotherapy research, 2020,34, 825-835. [23] Pulivendala G, Bale S, Godugu C. Honokiol: A polyphenol neolignan ameliorates pulmonary fibrosis by inhibiting TGF-/Smadsignaling, matrix proteins and IL-6/CD44/STAT3 axis both in vitro and in vivo. Toxicology and applied pharmacology 2020, 391, 114913. [24] Pulivendala G, Bale S, Godugu C. Inhalation of sustained release microparticles for the targeted treatment of respiratory diseases. Drug delivery and translational research 2020, 10, 339-353. [25] Saifi MA, Godugu C. Inhibition of lysyl oxidase ameliorates renal injury by inhibiting CD44-mediated pericyte detachment and loss of peritubular capillaries. Life sciences 2020, 243, 117294. [26]Sharma N, Saifi MA, Singh SB, Godugu C. In vivo studies: toxicity and biodistribution of nanocarriers in organisms. InNanotoxicity 2020, 41-70. [27] Thatikonda S, Pooladanda V, Godugu C. Repurposing an old drug for new use: Niclosamide in psoriasis-like skin inflammation. Journal of cellular physiology 2020, 235, 5270-5283. [28] Thatikonda S, Pooladanda V, Sigalapalli DK, Godugu C. Piperlongumine regulates epigenetic modulation and alleviates psoriasis-like skin inflammation via inhibition of hyperproliferation and inflammation. Cell death & disease 2020, 11, 21. [29] Anil K Kalvala, Veera Ganesh Yerra, Ashutosh Kumar. LONP1 induction by SRT1720 attenuates mitochondrial dysfunction against high glucose induced neurotoxicity in PC12 cells. Toxicology In Vitro 2020, 62, 104695 [30] Rathi S, Chavan RB, Shastri NR.Classification of the crystallization tendency of active pharmaceutical ingredients (APIs) and nutraceuticals based on their nucleation and crystal growth behaviour in solution state. Drug DelivTransl Res. 2020, 10, 70-82 [31] SanandaSom, Sachin Kumar Singh, Gopal L Khatik, Bhupinder Kapoor, Monica Gulati, GowthamarajanKuppusamy, Nandha Kumar Anandhakrishnan, Bimlesh Kumar, Ankit Kumar Yadav, Rajesh Kumar, Pankaj Kumar Singh, Rubiya Khursheed, Rajan Kumar, Narendra Kumar Pandey, Jivan Jyoti, SouvikMohanta, OmjiPorwal. Quality by Design-Based Crystallization of Curcumin Using Liquid Antisolvent Precipitation: Micromeritic, Biopharmaceutical, and Stability Aspects. ASSAY DRUG DEV TECHN. 2020, 18, 913-926 [32] Pankaj Kumar Singh, BapiGorain, Hira Choudhury, Sachin Kumar Singh, Pankaj Whadwa, Shilpa, Sanjeev Sahu, Monica Gulati, Prashant Keshrwani. Macrophage targeted amphotericin B nanodelivery systems against visceral leishmaniasis. Mater Sci Eng B. 2020, 258, 114571 [33]Raju Saka, Harsha Jain, NagavendraKommineni, Naveen Chella, Wahid Khan. Enhanced penetration and improved therapeutic efficacy of bexarotene via topical liposomal gel in imiquimod induced psoriatic plaque model in BALB/c mice. J DRUG DELIV SCI TEC. 2020, 58, 101691. [34] Pankaj Kumar Singh, BapiGorain, Hira Choudhury, Sachin Kumar Singh, Pankaj Whadwa, Shilpa, Sanjeev Sahu, Monica Gulati, Prashant Keshrwani. Macrophage targeted amphotericin B nanodelivery systems against visceral leishmaniasis. Mater Sci Eng B. 2020, 258, 114571. [35] Mani, G. S.; Anchi, P.; Sunkari, S.; Donthiboina, K.; Godugu, C.; Shankaraiah, N.; Kamal, A. Synthesis of (Z)-3-(arylamino)-1-(3-phenylimidazo[1,5-a]pyridin-1-yl)prop-2-en-1-ones as potential cytotoxic agents; Bioorg. Med. Chem. Lett2020, 30, 127432. [36] Laxmikeshav, K.; Sakla, A. P. Rasane, S.; John, S. E.; Shankaraiah, N. Microwave-assisted Regioselective Friedel-Crafts Arylation by BF3.OEt2: A Facile Synthetic access to 3-Substituted-3-Propargyl Oxindole Scaffolds; ChemistrySelect 2020, 5, 7004–7012. [37] Sana, S.; Reddy, V. G.; Bhandari, S.; Reddy, T. S.; Tokala, R.; Sakla, A. P.; Bhargava, S. K.; Shankaraiah, N. Exploration of Carbamide Derived Pyrimidine-Thioindole Conjugates as Potential VEGFR-2 Inhibitors with Anti-Angiogenesis Effect; Eur. J. Med. Chem2020, 200, 112457. [38] Bhandari, S.; Kulkarni, N.; Sakla, A. P.; Shankaraiah, N. Lewis acid-catalyzed dehydrative [3+2] cycloaddition reaction: A facile synthetic approach to spiro-benzoindoline oxindoles; Tetrahedron Lett2020, 61, 152007. [39] Dilep, K. S.; Raghu, R.; Neelima. D. T. Novel huperzine A based NMDA antagonists: insights from molecular docking, ADME/T and molecular dynamics simulation studies. RSC Advances2020, 10, 25446-25455. [40] Dilep, K. S.; Venkatesh, P.; Manasa, K.; Sravanthi, D. G.; Jaya Lakshmi, U.; Chandraiah, G.; Nagendra, B. B.; Neelima, D. T. Novel chromenyl-based 2-iminothiazolidin-4-one derivatives as tubulin polymerization inhibitors: Design, synthesis, biological evaluation and molecular modelling studies. J. Mol. Struct2020, 1225, 128847. [41] G.; Venkatesh, P.; Muni. K. C.; Lakshmi. S. P. S.; Ravi, A.; Pardeep, K.; Chandana, N.; Rose. D. B.; Insaf, A. Q.; Chandraiah, G.; Mallika, A. Novel benzimidazole-triazole hybrids as apoptosis inducing agents in lung cancer: Design, synthesis, 18F-radiolabeling & galectin-1 inhibition studies. Bioorg. Chem2020, 102, 104125. [42] Manasa, K. L.; Sowjanya, T.; Dilep, K. S.; Arpita, S.; Gaddam, K.; Arunasree, M. K.; Mallika, A.; Chandraiah, G.; Narayana, N.; Bathini, N. B. Design and Synthesis of β-carboline linked aryl sulfonyl piperazine derivatives: DNA topoisomerase II inhibition with DNA binding and apoptosis inducing ability. Bioorg. Chem2020, 101, 103983. [43] Priti, S.; Baijayantimala, S.; Pavitra, S. T.; Dilep, K. S.; Purnachander, Y. P.; Andrea, A.; Claudiu, T. S.; Mohammed, A. Synthesis and carbonic anhydrase inhibition studies of sulfonamide based indole-1,2,3-triazole chalcone hybrids. Bioorg. Chem., 2020, 99, 103839. [44] Pavitra, S. T.; Andrea, A.; Omkar, S. A.; Prerna, L. T.; Mohammed, A.; Claudiu, T. S. Design, synthesis and biological evaluation of coumarin linked 1,2,4-oxadiazoles as selective carbonic anhydrase IX and XII inhibitors. Bioorg. Chem2020, 98, 103739. [45] Andrea, A.; Priti, S.; Claudiu, T. S.; Mohammed, A. New coumarin/sulfocoumarin linked phenylacrylamides as selective transmembrane carbonic anhydrase inhibitors: Synthesis and in-vitro biological evaluation. Bioorg. Chem2020, 28, 115586. [46] Krishna, K. C.; Andrea, A.; Pavitra, S. T.; Laxman, N. K.; Rashmita, B.; Mohammed, A.; Claudiu, T. S. Design, Synthesis, and Biological Evaluation of 1,2,3-Triazole-Linked Triazino[5,6-B] Indole-Benzene Sulfonamide Conjugates as Potent Carbonic Anhydrase I, II, IX, and XIII Inhibitors. Metabolites2020, 10, 200. [47] Polymer-drug conjugates: recent advances and future perspectives. Drug Discovery Today. 2020, 1-10. [48] Harsha Jain, Arpita Bairagi, Saurabh Srivastava, Shashi Bala Singh, Neelesh Kumar Mehra. Recent advances in the development of microparticles for pulmonary administration. Drug Discovery Today. 2020, 1-10. [49] Rosenholm, Neelesh Kumar Mehra. Evolution of nanotechnology in delivering drugs to eyes, skin and wounds via topical route. Pharmaceuticals2020, 13, 167. [50] Lakshmi B, Kritika Aggarwal: Impact of Parent Brand On Brand Extension By Firm, European Journal Of Biomedical And Pharmaceutical Sciences 2020, 7, 2349-8870. [51] Lakshmi B, Sravani N.Sports medicine market – growth factors and forecasts. World Journal of Advanced Research and Reviews 2020, 7, 117-128. [52] Lakshmi B, Swapnil Patel. Digital Marketing in Pharmaceutical Industry –An Overview and Assessment, International Journal of Pharmaceutical Science & Innovation 2020, 1. [53] Kalvala AK, Yerra VG, Sherkhane B, Gundu C, Arruri V, Kumar R, et al. Chronic hyperglycemia impairs mitochondrial unfolded protein response and precipitates proteotoxicity in experimental diabetic neuropathy: focus on Lonp1 mediated mitochondrial regulation. Pharmacological Reports2020, 72, 1627-44 [54] Kalvala AK, Kumar R, Sherkhane B, Gundu C, Arruri VK, Kumar A, Bardoxolone Methyl Ameliorates Hyperglycemia Induced Mitochondrial Dysfunction by Activating the keap1-Nrf2-ARE Pathway in Experimental Diabetic Neuropathy. Mol. Neurobiol2020, 57, 3616-31. [55] Kalvala AK, Khan I, Gundu C, Kumar A. An Overview on ATP Dependent and Independent Proteases Including an Anterograde to Retrograde Control on Mitochondrial Function; Focus on Diabetes and Diabetic Complications. Curr. Pharm2019, 25, 2584-94. [56] Bheereddy P, Yerra VG, Kalvala AK, Sherkhane B, Kumar A. SIRT1 Activation by Polydatin Alleviates Oxidative Damage and Elevates Mitochondrial Biogenesis in Experimental Diabetic Neuropathy. Cellular and molecular neurobiology2020, 18, 1-5. [57] Kiran Jyoti, Garima Malik, Monika Chaudhary, Monika Sharma, Manish Goswami, Om Prakash Katare, Shashi Bala Singh, Jitender Madan. Chitosan and phospholipid assisted topical fusidic acid drug delivery in burn wound: Strategies to conquer pharmaceutical and clinical challenges, opportunities and future panorama. Int J BiolMacromol2020, 161, 325-335. [58] Diksha Gupta, Aishwarya Gangwar, Kiran Jyoti, Vaskuri G S Sainaga Jyothi, Rupinder Kaur Sodhi, Neelesh Kumar Mehra, Shashi Bala Singh, Jitender Madan. Self-healing hydrogels: A new paradigm immunoadjuvant for delivering peptide vaccine. Colloids Surf B Biointerfaces2020, 194, 111171. [59] Simerjeet Kaur Chahal, Rupinder Kaur Sodhi, Jitender Madan. Duloxetine hydrochloride loaded film forming dermal gel enriched with methylcobalamin and geranium oil attenuates paclitaxel-induced peripheral neuropathy in rats. IBRO Rep. 2020, 9, 85-95. [60] Madhu Ganesh, Jayashree R, Synthetic Organic Transformations of Transition Metal Nanoparticles as Propitious Catalysts: A Thumbnail, Asian Journal of Organic Chemistry, Accepted. [61] AkhilaMettu, VenuTalla, Subhashini James PrameelaNaikal. Novel anticancer Hsp90 inhibitor disubstituted pyrazolyl 2-aminopyrimidine compound 7t induces cell cycle arrest and apoptosis via mitochondrial pathway in MCF-7 cells, Bioorganic & Medicinal Chemistry Letters2020, 30, 127470 [62] Chauhan N R , Kumar R , Gupta A , Meena RC, Nanda S, Mishra KP, Singh SB, Heat Stress-induced oxidative damage and perturbation in BDNF/ERK1/2/CREB axis in hippocampus impairs spatial memory. Behav Brain Res. 2020, Accepted. [63] Valamla Bhavana, Pradip Thakor, Shashi BalaSingh, Neelesh Kumar Mehra. COVID-19: Pathophysiology, treatment options, nanotechnology approaches, and research agenda to combating the SARS-CoV2 pandemic. Life Sciences. 2020. Accepted [64] Suranjana Sen, Tammanna R Sahrawat, Shashi Bala Singh, Bhuvnesh Kumar, Madhusudan Pal. Determination of most important predictor of Vertical Ground Reaction Force (VGRF) and threshold value of fracture among young adults. Ameen J.Med.Sci. 2020, 13,162-171 [65] Priya Gaur, Supriya Saini, Koushik Ray, KushubakovaNadiraAsanbekovna, AlmazAkunov, AbdirashitMaripov, AkpaySarybaev, Shashi Bala Singh, Bhuvnesh Kumar, Praveen Vats. Temporal transcriptome analysis suggest modulation of multiple pathways and gene network involved in cell-cell interaction during early phase of high altitude exposure. PlosOne,2020, 1-26 [66] Jadala, C.; Reddy, V. G.; Krishna, N. H.; Shankaraiah, N.; Kamal, A, Base-mediated 1,3-dipolar cycloaddition of pyridinium bromides with bromoallyl sulfones: a facile access to indolizine scaffolds;. Org. Biomol. Chem2020, 18, 8694-8701. [67]Sakla, A. P.; Kansal, P.; Shankaraiah, N.Syntheses and reactivity of spiro-epoxy/aziridine oxindole cores: developments in the past decade; Org. Biomol. Chem2020, 18, 8572–8596. [68] Tokala, R.; Sana, S.; Lakshmia, U. J.; Sankarana, P.; Sigalapalli, D. K.; Gadewal, N.; Kode, J.; Shankaraiah, N. Design and synthesis of thiadiazolo-carboxamide bridged β-carboline-indole hybrids: DNA intercalative topo-IIα inhibition with promising antiproliferative activity; Bioorg. Chem. 2020, 105, 104357 [69] Shinde, S. D.; Sakla, A. P. Shankaraiah, N, An Insight into Medicinal Attributes of Dithiocarbamates: Bird’s Eye View;.Bioorg. Chem. 2020, 105, 104346 [70] Donthiboina, K.; Anchi, P.; Gurram, S.; Mani, G. S.; Uppu, J. L.; Godugu, C.; Shankaraiah, N.; Kamal, A. Synthesis and biological evaluation of substituted N-(2-(1H-benzo[d]imidazol-2-yl)phenyl)cinnamides as tubulin polymerization inhibitors; Bioorg. Chem. 2020, 103, 104191 [71] Kumar M, Madan J, Sodhi RK, Singh SB, Katyal A. Decoding the silent walk of COVID-19: Halting its spread using old bullets. Biomed Pharmacother. 2021, 133, 110891. [72] Jyoti K, Katare OP, Kamboj A, Madan J. Protamine sulphate coated poly (lactide-co-glycolide) nanoparticles of MUC-1 peptide improved cellular uptake and cytokine release in mouse antigen presenting cells. J Microencapsul. 2020, 37, 566-576. [73] Sethi S, Choudhary S, Sharma D, Jyothi VGS, Baldi A, Mehra NK, Madan J. Armamentarium of anticancer analogues of curcumin: Portray of structural insight, bioavailability, drug-target interaction and therapeutic efficacy. J. Molecular Structure. 2020, 129691. [74] Sondhi S, Kaur R, Madan J. Purification and characterization of a novel white highly thermo stable laccase from a novel Bacillus sp. MSK-01 having potential to be used as anticancer agent. Int J BiolMacromol. 2020, 170, 232-238.

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Euphrem Ndayiragije


Works at Universite du Burundi Attended National Institute of Pharmaceutical Education and Research, Hyderabad, India under Student Exchange Progrm Lives in Bujumbura, Burundi Republic of Burundi

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India is home to 40 UNESCO World Heritage Sites out of which there are 32 cultural, 7 natural and 1 mixed property.